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Publicaciones / Papers

 

  1. Lapponi, MJ; Rivero, CW.; Britos, CN; Trelles, JA; 2025. Optimized cladribine bioproduction using Arthrobacter oxydans immobilized on alginate-bentonite beads. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 136998. https://doi.org/10.1016/j.colsurfa.2025.136998

  2. Lapponi, MJ; Méndez, MB; Trelles, JA; Rivero, CW. 2022. Cell immobilization strategies for biotransformations. Current Opinion in Green and Sustainable Chemistry, 33:100565. https://doi.org/10.1016/j.cogsc.2021.100565

  3. Rivero, CW; García, NS; Fernández-Lucas, J; Betancor, L; Romanelli, GP; Trelles, JA. 2021. Green production of cladribine by using immobilized 2-deoxyribosyltransferase from Lactobacillus delbrueckii stabilized through a double covalent/entrapment technology. Biomolecules, 11 (5), 657. https://doi.org/10.3390/biom11050657

  4. Gianolini, JE; Britos, CN; Mulreedy, C; Trelles, JA. 2020. Hyperstabilization of a thermophile bacterial laccase and its application for industrial dyes degradation. 3 Biotech, 10. https://doi.org/10.1007/s13205-020-02277-3

  5. Lappaset Laumann, AS; Britos, CN; Cappa, VA; Rivero, CW; Trelles, JA. 2020. Biotransformation of cladribine by a magnetic immobilized biocatalyst of Lactobacillus animalis. Biotechnology Letters. https://doi.org/10.1007/s10529-020-02845-w

  6. Méndez, M; Trelles, JA; Rivero, CW. 2020. Decitabine bioproduction using a biocatalyst with improved stability by adding nanocomposites. AMB Express, 10:173. https://doi.org/10.1186/s13568-020-01109-0

  7. Rivero, CW; De Benedetti, EC; Sambeth, J; Trelles, JA. 2020. Biotransformation of cladribine by a nanostabilized extremophilic biocatalyst. Journal of Biotechnology, 323: 166-173. https://doi.org/10.1016/j.jbiotec.2020.08.012

  8. Trelles, JA; Rivero, CW. 2020. Whole cell entrapment techniques. In Guisán, J; Bolivar, J; López-Gallego, F; Rocha-Martín, J (eds). Immobilization of enzymes and cells, Methods in Molecular Biology, vol 2100, pp 385-394. Humana, New York, NY.

  9. Lapponi, MJ; Britos, CN; Rivero, CW; Trelles, J. 2019. Biotransformation of cladribine using a stabilized biocatalyst in calcium alginate beads. Biotechnology Progress. https://doi.org/10.1002/btpr.2927

  10. Britos, CN; Gianolini, JE; Portillo, H; Trelles, J. 2018. Biodegradation of industrial dyes by a solvent, metal and surfactant-stable extracellular bacterial laccase. Biocatalysis and Agricultural Biotechnology, 14: 221-227. https://doi.org/10.1016/j.bcab.2018.03.015

  11. Méndez, M; Rivero, CW; López Gallego, F; Guisán, JM; Trelles, J. 2018. Development of a high efficient biocatalyst by oriented covalent immobilization of a novel recombinant 2'-N-deoxyribosyltransferase from Lactobacillus animalis. Journal of Biotechnology, 270: 39-43. https://doi.org/10.1016/j.jbiotec.2018.01.011

  12. Ramirez Tapias, YA; Rivero, CW; Giraldo Estrada, C; Britos, CN; Trelles, J. 2018. Biodegradation of vegetable residues by polygalacturonase-agar using a trickle-bed bioreactor. Food and Bioproducts Processing, 111: 54-61. https://doi.org/10.1016/j.fbp.2018.06.006

  13. Sarquiz, A; Rivero, CW; Britos, CN; Trelles, J. 2018. Biotransformation of 5'-O-β-D-galactosyl-floxuridine by immobilized β-galactosidase from Kocuria rhizophila. Journal of Fluorine Chemistry, 214: 58-62. https://doi.org/10.1016/j.jfluchem.2018.07.012

  14. Trelles, JA; Rivero, CW; Britos, CN; Lapponi, MJ. 2018. Enzymatic synthesis of nucleic acid derivatives by immobilized cells. In Fernández-Lucas, J (ed). Enzymatic and chemical synthesis of nucleic acid derivatives, pp 79-106. Wiley-VCH. https://doi.org/10.1002/9783527812103.ch4

  15. Cappa, VA; Trelles, JA. 2017. One-pot biosynthesis of idoxuridine using nanostabilized lactic acid bacteria. Process Biochemistry, 62: 169-173. https://doi.org/10.1016/j.procbio.2017.07.028

  16. Etcheverry, M; Cappa, VA; Trelles, JA; Zanini, G. 2017. Montmorillonite-alginate beads: Natural mineral and biopolymers based sorbent of paraquat herbicides. Journal of Environmental Chemical Engineering, 5 (6): 5868-5875. https://doi.org/10.1016/j.jece.2017.11.018

  17. Fernández-Brando, R; Amaral, MM; Ciocchini, AE; Bentancor, LV; Trelles, JA; Da Rocha, M; Landriel, M; Ugarte, M; Britones, G; Ibarra, C; Palermo, MS. 2017. Microbiological and serological control of Escherichia coli O7:H157 in kindergarten staff in Buenos Aires city and suburban areas. Medicina (Buenos Aires), 77 (3): 185-190. https://www.medicinabuenosaires.com/PMID/28643674.pdf

  18. Ramirez Tapias, YA; Lapasset Laumann, AS; Britos, CN; Rivero, CW; Trelles, JA. 2017. Saccharification of citrus wastes by immobilized polygalacturonase in an improved alginate matrix. 3 Biotech, 7 (6): 380. 10.1007/s13205-017-1010-4

  19. Rivero, CW; De Benedetti, EC; López Gallego, F; Pessela, BC; Guisán, JM; Trelles, JA. 2017. Biosynthesis of an antiviral compound using a stabilized phosphopentomutase by multipoint covalent immobilization. Journal of Biotechnology, 249: 34-41. https://doi.org/10.1016/j.jbiotec.2017.03.027

  20. Trelles, JA; Lapponi, MJ. 2017. Immobilization techniques applied to the development of biocatalysts for the synthesis of nucleoside analogue derivatives. Current Pharmaceutical Design, 23 (45): 6903-6921. 10.2174/1381612824666171204102204

  21. Britos, CN; Lapponi, MJ; Cappa, VA; Rivero, CW; Trelles, JA. 2016. Biotransformation of halogenated nucleosides by immobilized Lactobacillus animalis 2´-N-deoxyribosyltransferase. Journal of Fluorine Chemistry, 186: 91-96. https://doi.org/10.1016/j.jfluchem.2016.04.012

  22. Britos, CN; Trelles, JA. 2016. Development of strong enzymatic biocatalysts for dye decolorization. Biocatalysis and Agricultural Biotechnology, 7: 228-233. https://doi.org/10.1016/j.bcab.2016.06.009

  23. Cappa, VA; Rivero, CW; Sambeth, JE; Trelles, JA. 2016. Bioproduction of floxuridine using nanostabilized biocatalysts. Chemical Engineering Technology, 39: 1723-1730. https://doi.org/10.1002/ceat.201500522

  24. Lapponi, MJ; Rivero, CW; Zinni, MA; Britos, CN; Trelles, JA. 2016. New developments in nucleoside analogues biosynthesis: A review. Journal Molecular Catalysis B: Enzymatic, 133: 218-233. https://doi.org/10.1016/j.molcatb.2016.08.015

  25. Ramírez Tapías, YA; Rivero, CW; López Gallego, L; Guisán, JM; Trelles, JA. 2016. Stabilization by multipoint covalent attachment of a biocatalyst with polygalacturonase activity used for juice clarification. Food Chemistry, 208: 252-257. https://doi.org/10.1016/j.foodchem.2016.03.086

  26. De Benedetti, EC; Rivero, CW; Trelles, JA. 2015. Development of a nanostabilized biocatalyst using an extremophilic microorganism for ribavirin biosynthesis. Journal Molecular Catalysis B: Enzymatic, 121: 90-95. https://doi.org/10.1016/j.molcatb.2015.08.006

  27. Ramírez Tapías, YA; Rivero, CW; Britos, CN; Trelles, JA. 2015. Alkaline and thermostable polygalacturonase from Streptomyces halstedii ATCC 10897 with applications in waste waters. Biocatalysis and Agricultural Biotechnology, 4: 221-228. https://doi.org/10.1016/j.bcab.2014.12.004

  28. Rivero, CW; De Benedetti, EC; Lozano, ME; Trelles, JA. 2015. Bioproduction of ribavirin by green microbial biotransformation. Process Biochemistry, 50: 935-940. https://doi.org/10.1016/j.procbio.2015.03.015

  29. Cappa, VA; Rivero, CW; Britos, CN; Martinez, LM; Lozano, ME; Trelles, JA. 2014. An efficient biocatalytic system for floxuridine biosynthesis based on Lactobacillus animalis ATCC 35046 immobilized in SR-alginate. Process Biochemistry, 49 (7): 1169–1175. https://doi.org/10.1016/j.procbio.2014.03.029

  30. Trelles, JA; Rivero, CW. 2013. Whole cell entrapment techniques. In Guisán, J (ed). Immobilization of enzymes and cells, Methods in Molecular Biology (Methods and Protocols), vol 1051, pp 365-374. Humana Press, Totowa, NJ.

  31. Britos, CN; Cappa, VA; Rivero, CW; Sambeth, JE; Lozano, ME; Trelles, JA. 2012. Biotransformation of halogenated 2’-deoxyribosides by immobilized lactic acid bacteria. Journal Molecular Catalysis B: Enzymatic, 79: 49-53. https://doi.org/10.1016/j.molcatb.2012.04.004

  32. De Benedetti, EC; Rivero, CW; Britos, CN; Lozano, ME; Trelles, JA. 2012. Biotransformation of 2,6-diaminopurine nucleosides by immobilized Geobacillus stearothermophilus. Biotechnology Progress, 28 (5): 1251-1256. https://doi.org/10.1002/btpr.1602

  33. Rivero, CW; Britos, CN; Lozano, ME; Trelles, JA. 2012. Green biosynthesis of floxuridine by immobilized microorganisms. FEMS Microbiology Letters, 331(1): 31-6. https://doi.org/10.1111/j.1574-6968.2012.02547.x

  34. Rivero, CW; De Benedetti, EC; Sambeth, JE; Lozano, ME; Trelles, JA. 2012. Biosynthesis of anti-HCV compounds using thermophilic microorganisms. Bioorganic and Medicinal Chemistry Letters, 22 (19): 6059-6062. https://doi.org/10.1016/j.bmcl.2012.08.045

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